Dr. Mahmud HASSAN

Dr. Mahmud HASSAN

Postdoctoral Researcher

Ph.D. in Plant Genome Engineering, University of Melbourne, Austrlaia (2018)

M.S. in Genetics and Plant Breeding, Bangladesh Agricultural University, Bangladesh (2010)

B.Sc. in Agricultural Science, Patuakhali Science and Technology University, Bangladesh (2008)

April 2018-Present: Postdoctoral Researcher, Bioscience Division, Oak Ridge National Laboratory, USA. 

May 2012-Present: Assistant Professor, Department of Genetics and Plant Breeding, Patuakhali Science and Technology University, Bangladesh. 

  • Genome Engineering
  • Synthetic Biology
  • Metabolic Engineering
  • Genome Security
  • Protein Trafficking


2015: Faculty of Science Abroad Travelling Scholarship, awarded by the University of Melbourne.

2015: Botany Foundation Travel Scholarship, awarded by the Botanical Society of Australia.

2013: Genetics Research Award, awarded by the University of Melbourne, Australia.

2013: Melbourne International Research Scholarship, awarded by the University of Melbourne, Australia.

2013: Melbourne International Fee Remission Scholarship, awarded by University of Melbourne, Australia.

2013: Chancellor’s Gold Medal, awarded by Patuakhali Science and Technology University (PSTU) for achieving the highest grade in the faculty during the undergraduate study.

2009: National Science Information and Communication Technology (NSICT) Fellowship, awarded by the Ministry of National Science Information and Communication Technology, Bangladesh for masters thesis research project.

2008: UGC merit scholarship, awarded by the University Grants Commission of Bangladesh, for achieving the highest grade in the faculty during the undergraduate study.

Oak Ridge National Laboratory
Postdoctoral Researcher

Current Research

  • Deliver biomolecules (DNA, Protein) to plant and human cells via cell-penetrating peptides
  • Engineering CAM (Crassulacean acid metabolism) pathway in C3 plants
  • Metabolic engineering in bacteria for CO2 fixation
  • Characterization of protein movement from plant to ectomycorrhizal fungi
  • Improving the safety of genome editing using CRISPR-Cas technology
  • Developing CRISPR technologies for non-model fungi


Previous Research

  • Develop targeted gene insertion technology for plants
  • Develop novel strategy to improve germline transformation in plant
  • Develop open source gene technology for developing nation



Peer-reviewed articles

Hassan MM, Yuan G, Chen J-G, Tuskan GA, and Yang X. 2020. Principles and technical aspects of
construct design of CRISPR-Cas based genome editing in plants.  (In preparation)

Yuan G, Hassan MM, Liu D, Cushman JC, Lu H, Chen J-G, Tschaplinski TJ, Tuskan GA, and Yang X. 2020.
Biosystem design to accelerate C3 to CAM evolution. BioDesign Res. (Submitted).

Hassan MM, Yuan G, Chen J-G, Tuskan GA, and Yang X. 2020. Prime editing technology and its prospect
for future applications in plant biology research. BioDesign Res. (Accepted)

Haque E†, Taniguchi H†, Hassan MM†, Bhowmik P, Karim MR, Smiech M, Zhao K, Rahman M and Islam T .
2018. Application of CRISPR/Cas9 Genome Editing Technology for the Improvement of Crops Cultivated
in Tropical Climates: Recent Progress, Prospects, and Challenges. Front. Plant Sci. 9:617. doi:10.3389/fpls.
2018.00617 (equal contributor author).

Hassan MN, Haque MS, Hassan MM, and Haque MS. 2014. An ecient protocol for somatic embryogenesis
of garlic (Allium sativum L.) using root tip as explant. J. Bangladesh Agril. Uni. 12 (1): 1-6. Doi:

Hassan MM, Shamsuddin AKM, Islam MM, Khatun K and Halder J. 2012. Analysis of genetic diversity
and population structure of some Bangladeshi rice landraces and HYV. J. Sci. Res. 4 (3): 757-767. Doi:

Emon RM, Gustafson JP, Nguyen H, Musket T, Jahiruddin M, Islam MA, Haque MS, Islam MM, Begum SN
and Hassan MM. 2010. Molecular marker-based characterize- ation and genetic diversity of wheat
genotypes in relation to born use eciency. Indian J. Genet. Plant Breed. 70 (4): 339-348.

Jewel AA, Alam AKMM, Latif MA, Chowdhury AK and Hassan MM. 2010. Multivariate analysis in
lentil (Lens culinaris). Bangladesh J. Plant Breed. Genet. 23 (1): 09-12.Doi:


Peer-reviewed book chapters

Bhowmik P, Hassan MM, Uddin K, and Islam T. 2018. Application of CRISPR-Cas9 genome editing tool for the improvement of plant abiotic stress tolerance. In Approaches for Enhancing Abiotic Stress Tolerance in Plants. CRC Press, Taylor and Francis Group. DOI: 10.1201/9781351104722-26


Conference presentation

Hassan MM, William A, Robin C, Russell DA and  Golz JF (2017). Development of
a germline-specific gene targeting system for Arabidopsis and Brassica species. 5th Plant Genome and
Gene Editing Congress. Amsterdam, Netherland.

Hassan MM,  Zaw  A and Golz JF (2016). Improving the efficiency of female germline transformation
in Canola. Poster presented at the Brassica2016 conference, Melbourne, Australia.

Hassan MM and Golz JF (2015) Engineering flower structure for germline transformation of
Brassica species. Combio2015 conference. Melbourne, Australia.